Cell Culture Media, Supplements, and Reagents
Apexbio Technology LLC Ionomycin free acid(Synonyms: Ionomycin (free acid), Antibiotic SQ 23377, SQ 23377, Calcium ionophore ionomycin), 5mg, CAS: 56092-81-0.
Ionomycin free acid (CAS 56092-81-0) is a selective calcium ionophore functioning by mediating Ca transport across biological membranes It forms complexes with calcium ions facilitating their passage through lipid bilayers and increasing intracellular Ca concentrations In vitro studies demonstrate its capacity to transfer calcium ions from aqueous to organic phases highlighting its ion carrier function In vivo experiments indicate ionomycin effectively activates mammalian oocytes promoting subsequent embryonic development Clinical research has employed ionomycin to assess improvements in fertilization outcomes for patients with decreased ovarian reserves
Apexbio Technology LLC Norfloxacin 70458-96-7 5g
Norfloxacin (70458-96-7) is a small-molecule inhibitor targeting bacterial DNA gyrase It is designed to inhibit DNA gyrase thereby interfering with bacterial DNA replication and transcription Norfloxacin exerts its biological activity primarily through inhibition of topoisomerase activity by binding to bacterial DNA gyrase disrupting DNA supercoiling and strand separation Norfloxacin demonstrates broad-spectrum antibacterial inhibition with reported IC50 values ranging from approximately 0 1 to 10 M depending on bacterial species and assay conditions Based on these pharmacological properties norfloxacin holds research potential in studies of bacterial DNA replication mechanisms antimicrobial susceptibility assays and resistance analyses
Apexbio Technology LLC Tylosin tartrate 74610-55-2 50mg
Tylosin tartrate (CAS 74610-55-2) is a small-molecule inhibitor targeting the bacterial 50S ribosomal subunit It is designed to inhibit bacterial protein synthesis thereby disrupting peptide elongation during translation Tylosin tartrate exerts its biological activity primarily through reversible binding to the 50S ribosomal subunit In microbiological assays tylosin tartrate demonstrates antibacterial activity with IC50 values typically ranging from 0 01 to 0 1 g/mL against mycoplasma strains depending on strain sensitivity Based on these pharmacological properties tylosin tartrate holds research potential in the investigation of antimicrobial mechanisms resistance profiles and bacterial physiology associated with poultry and livestock infections
Apexbio Technology LLC Levofloxacin 100986-85-4 5g
Levofloxacin (CAS 100986-85-4) is a small-molecule inhibitor targeting bacterial DNA gyrase (topoisomerase II) It modulates DNA supercoiling thereby regulating DNA replication and transcription in bacteria Levofloxacin exerts its biological activity primarily through stabilization of the DNA enzyme cleavage intermediate interfering with DNA replication and causing bacterial cell death In in vitro studies Levofloxacin demonstrates antibacterial inhibitory activity with IC50 values typically ranging from approximately 0 5 g/mL to 4 g/mL depending on bacterial species and experimental conditions Based on these pharmacological properties Levofloxacin holds research potential in studies involving bacterial susceptibility profiling and the development of antibiotic resistance
Medchemexpress LLC HY-16973 100mg Medchemexpress, Fluralaner CAS:864731-61-3 Purity:>98%
Medchemexpress, HY-16973 100mg Fluralaner CAS:864731-61-3 Fluralaner (INN) is a systemic insecticide and acaricide Fluralaner through potent blockage of GABA and L-glutamate gated chloride channels. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Selleck Chemical LLC Cephalothin sodium S4594-100mg
Cephalothin (Cefalotin Cephalotin) sodium is a semisynthetic beta-lactam first-generation cephalosporin antibiotic with bactericidal activity Cephalothin binds to and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall
Selleck Chemical LLC Amikacin disulfate S3065-200mg
Amikacin sulfate (BB-K8) binds to 16S rRNA (bacterial 30S ribosome) causing misreading of mRNA and supressing proteins synthesis
Medchemexpress LLC HY-B2148 100mg Medchemexpress, Myclobutanil CAS:88671-89-0 Purity:>98%
Medchemexpress, HY-B2148 100mg Myclobutanil CAS:88671-89-0 Myclobutanil is a conazole class fungicide widely used as an agrichemical. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC (±)-Baclofen 1134-47-0 5g
( )-Baclofen (CAS 1134-47-0) is a selective agonist of the -aminobutyric acid type B (GABAB) receptor a G protein-coupled receptor involved in inhibitory neurotransmission Exhibiting an IC50 of 200 nM ( )-baclofen induces skeletal muscle relaxation and reduces spasticity by activating GABAB-mediated signaling pathways In cellular studies ( )-baclofen inhibits the proliferation of human hepatocellular carcinoma (HCC) cells in a dose-dependent manner induces G0/G1 cell cycle arrest and modulates intracellular cAMP and p21WAF1 expression In vivo it suppresses tumor growth in HCC xenograft models without evident toxicity ( )-Baclofen is thus valuable for investigating GABAB-mediated mechanisms in cancer and neuropharmacology
Medchemexpress LLC Valspodar | 121584-18-7 | 99.3% | 1214.62 | 1 MG
Valspodar (PSC 833) is a selective P-glycoprotein inhibitor that has been used as an experimental cancer treatment and chemosensitizer.
- Solid appearance, white to yellow color
- Ships at room temperature in continental US
- Store powder at -20°C for 3 years, or in solvent at -80°C for 6 months / -20°C for 1 month
- Soluble in DMSO at 100 mg/mL (82.33 mM)
- Exhibits no cytotoxicity effects up to 0.75 μg/mL
- Increases cell kill efficacy of MDR cell type when administered with DOX-L
- Displays slow clearance and large volume of distribution in vivo
- Shows low hepatic extraction and wide distribution similar to CsA in vivo
Cayman Chemical UracIl-13C4 15N2 5mg
An internal standard for the quantification of uracil by GC- or LC-MS
Crescent Chemical Co Inc STREPTOMYCIN SULFATE
Streptomycin sulfate research grade, Ph. Eur. Min. 720 U/mg. Aminoglycoside antibiotic from Streptomyces griseus. Blocks the initiation complex and causes misreading on ribosomes in protein synthesis. Inhibits function only of the 30S subunit. Size - 10G Stor
Medchemexpress LLC HY-P7312 10ug Medchemexpress, VEGF165, Mouse CAS: Purity:>98%
Medchemexpress, HY-P7312 10ug VEGF165, Mouse CAS: Recombinant Mouse VEGF165 is a potent mediator of angiogenesis and binds the semaphorin receptor, neuropilin1. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-W017162 100mg Medchemexpress, DL-3-Phenyllactic acid CAS:828-01-3 Purity:>98%
Medchemexpress, HY-W017162 100mg DL-3-Phenyllactic acid CAS:828-01-3 DL-3-Phenyllactic acid is a broad-spectrum antimicrobial compound. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.